مجله علوم و صنایع غذایی ایران

مجله علوم و صنایع غذایی ایران

Modulating the Stress Axis and Cellular Thermotolerance in Shami Goat Bucks: Dietary Ginseng Powder as a Strategy to Enhance Climatic Resilience

نوع مقاله : مقاله پژوهشی

نویسنده
College of Health and medical techniques ,Al-Zahrawi University , Karbala, Iraq.
10.48311/fsct.2026.118563.83008
چکیده
The Shami goat breed represents an economically important livestock resource in the Middle East, yet environmental stressors and intensive management systems can compromise reproductive performance through dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Ginseng (Panax ginseng C.A. Meyer), recognized for its adaptogenic properties, has shown promise in modulating stress responses and cellular protective mechanisms. This study investigated the effects of dietary ginseng powder supplementation on cortisol, adrenocorticotropic hormone (ACTH), heat shock proteins (HSP70 and HSP90), and reproductive performance parameters in Shami goat bucks. Twenty-four mature Shami bucks (2-3 years old, 45-55 kg body weight) were randomly allocated to four treatment groups (n=6 per group): control (basal diet), and three ginseng supplementation levels (1, 2, and 3 g/kg diet) for 90 days. Blood samples were collected bi-weekly for hormonal and HSP analysis. Semen quality, testicular measurements, and libido scores were evaluated throughout the experimental period. Ginseng supplementation demonstrated dose-dependent effects on HPA axis regulation. The 2 g/kg treatment group showed significantly reduced serum cortisol (32.4 ± 2.1 ng/mL vs. 48.7 ± 3.4 ng/mL in control, P < 0.01) and ACTH levels (28.6 ± 1.8 pg/mL vs. 42.3 ± 2.9 pg/mL in control, P < 0.01). HSP70 expression increased by 47% (P < 0.05) while HSP90 showed moderate elevation (23%, P<0.05) in the optimal treatment group. Sperm concentration improved from 2.8 ± 0.3 × 10⁹/mL (control) to 3.9 ± 0.2 × 10⁹/mL (2 g/kg group, P < 0.01), with corresponding improvements in motility (68.4 ± 3.2% vs. 79.8 ± 2.1%, P<0.01) and morphology.
کلیدواژه‌ها

موضوعات


عنوان مقاله English

Modulating the Stress Axis and Cellular Thermotolerance in Shami Goat Bucks: Dietary Ginseng Powder as a Strategy to Enhance Climatic Resilience

نویسنده English

Heba A Abd-Alsalam Alsalame
College of Health and medical techniques ,Al-Zahrawi University , Karbala, Iraq.
چکیده English

The Shami goat breed represents an economically important livestock resource in the Middle East, yet environmental stressors and intensive management systems can compromise reproductive performance through dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Ginseng (Panax ginseng C.A. Meyer), recognized for its adaptogenic properties, has shown promise in modulating stress responses and cellular protective mechanisms. This study investigated the effects of dietary ginseng powder supplementation on cortisol, adrenocorticotropic hormone (ACTH), heat shock proteins (HSP70 and HSP90), and reproductive performance parameters in Shami goat bucks. Twenty-four mature Shami bucks (2-3 years old, 45-55 kg body weight) were randomly allocated to four treatment groups (n=6 per group): control (basal diet), and three ginseng supplementation levels (1, 2, and 3 g/kg diet) for 90 days. Blood samples were collected bi-weekly for hormonal and HSP analysis. Semen quality, testicular measurements, and libido scores were evaluated throughout the experimental period. Ginseng supplementation demonstrated dose-dependent effects on HPA axis regulation. The 2 g/kg treatment group showed significantly reduced serum cortisol (32.4 ± 2.1 ng/mL vs. 48.7 ± 3.4 ng/mL in control, P < 0.01) and ACTH levels (28.6 ± 1.8 pg/mL vs. 42.3 ± 2.9 pg/mL in control, P < 0.01). HSP70 expression increased by 47% (P < 0.05) while HSP90 showed moderate elevation (23%, P<0.05) in the optimal treatment group. Sperm concentration improved from 2.8 ± 0.3 × 10⁹/mL (control) to 3.9 ± 0.2 × 10⁹/mL (2 g/kg group, P < 0.01), with corresponding improvements in motility (68.4 ± 3.2% vs. 79.8 ± 2.1%, P<0.01) and morphology.

کلیدواژه‌ها English

Panax ginseng
adaptogen
cortisol
stress physiology
semen quality
goat breeding
sustainable production
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