Volume 19, Issue 123 (2022)
FSCT 2022, 19(123): 81-91 |
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shirani K, safaeian S, mousavi nadushan R, Rahimifard N. Evaluation of phytochemical compounds and antioxidant properties of Padina distromatic and Sargassum angustifulium Ultrasound extracts. FSCT 2022; 19 (123) :81-91
URL: http://fsct.modares.ac.ir/article-7-57812-en.html
URL: http://fsct.modares.ac.ir/article-7-57812-en.html
1- Department of Food Science and Technology, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran.
2- Department of Food Science and Technology, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran. ,safaeian.shilla1400@gmail.com
3- Food and Drug Control Laboratories, Ministry of Health and Medical Education, Tehran, Iran.
2- Department of Food Science and Technology, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran. ,
3- Food and Drug Control Laboratories, Ministry of Health and Medical Education, Tehran, Iran.
Abstract: (1863 Views)
In recent decades, the demand for the use of functional compounds in food and pharmaceutical products has increased. The aim of this study was to compare the phytochemical compounds and antioxidant, anti-Alzheimer's and antimicrobial properties of Padina distromatic and Sargassum angustifulium algae extracted by ultrasound. The results showed that butanoic acid was the most important substance in Padina and Sargasum extracts. Total content of polyphenols, flavonoids and IC50 index of Padina extract and sargasum 43.45 and 46.63 mg GAE/g, flavonoid content 24.59 and 55.40 mg QE/g and IC50 index 10.38 and 30.77 g/ml respectively. The inhibitory activity of acetylcholinesterase (AChE) of Padina and Sargassum algae extracts was 42.5% and 25.16%, respectively. Nitric oxide (NO) inhibitory results showed that nitric oxide inhibitory activity increased with increasing the concentration of both Padina and Sargassum algae extracts (from 50 to 400 mg / ml). However, Padina algae extract had the strongest NO inhibitory activity at all concentrations. Padina extract had more antimicrobial properties compared to the algae extract of sargassum. The minimum inhibitory concentration (MIC) of Padina extract at 12.5 mg/ml was obtained on Staphylococcus aureus. Padina extract at 50 mg/ml had a bactericidal effect on Staphylococcus aureus. Finally, Sargassum extract should be used as natural antioxidant and Padina extract as natural anti-Alzheimer's and antimicrobial components.
Keywords: Antioxidant, Brown marine algae, Functional component, Ultrasound, Anti-microbial properties.
Article Type: Original Research |
Subject:
Extraction of effective compounds
Received: 2021/12/12 | Accepted: 2022/01/24 | Published: 2022/05/4
Received: 2021/12/12 | Accepted: 2022/01/24 | Published: 2022/05/4
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