Volume 18, Issue 117 (2021)                   FSCT 2021, 18(117): 277-287 | Back to browse issues page

‎ 10.52547/fsct.18.117.277

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Mortazavi S A, mohebbi M, Bagheri A. Production of curcumin-loaded lipid nanocarriers and assessment of its qualitative characteristic. FSCT 2021; 18 (117) :277-287
URL: http://fsct.modares.ac.ir/article-7-12969-en.html
Production of curcumin-loaded lipid nanocarriers and assessment of its qualitative characteristic
Sayed Ali Mortazavi1 , Mohebbat Mohebbi1 , Abdolreza Bagheri2
1- Department of Food Science and Technology, Ferdowsi University of Mashhad, PO Box 91775-1163, Mashhad, Iran.
2- Department of Plant Biotechnology and Breeding
Abstract:   (2049 Views)
Abstract Solid lipid nanoparticles and nanostructure lipid carriers were used to entrap curcumin and broaden confined knowledge of application of nanocarriers as the functional ingredients in food sectors. The effect of lipids ratio (GDS /GMS), kind of nanocarrier (SLN and NLC) and curcumin concentration (0, 0.25 and 0. 5 % (w / w) of emulsion) on the qualitative characteristics of nanocarrier were evaluated. Based on the results the massive physical structure of Curcumin and also increases the viscosity of the material dispersed phase in the presence of active, loading Curcumin in the developed nanocarrier led to significant (p<0.05) increase in nanoparticles size. DSC analyses showed that the crystalline states of produced nanocarriers were less ordered than pure materials and indicated that the curcumin was well incorporated in lipid matrices. However, our pretest showed that concentration of 5% Glycerol distearate and 0.25% Curcumin was the optimum for the production of Solid lipid nanoparticles and nanostructure lipid carriers.
Keywords: Curcumin, Nanostructure lipid carriers, Solid lipid nanocarriers
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Article Type: Original paper | Subject: Food quality control
Received: 2016/03/7 | Accepted: 2021/11/1 | Published: 2021/11/1
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