Alizadeh behbahani B, Golbashy M. Evaluation of the antimicrobial activity of dill aqueous extract and its interaction with chloramphenicol antibiotic: An in vitro study. FSCT 2025; 22 (161) :275-285
URL:
http://fsct.modares.ac.ir/article-7-79021-en.html
1- Associate Professor, Department of Food Science and Technology, Faculty of Animal Science and Food Technology, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Iran. , behrooz66behbahani@gmail.com
2- Assistant Professor, Department of Plant Production and Genetics, Faculty of Agriculture, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Iran.
Abstract: (84 Views)
Dill (Anethum graveolens) is a traditional medicinal plant widely used for the treatment of various diseases. In this study, the antibacterial potential of dill leaf aqueous extract against Erwinia amylovora, Pseudomonas syringae, Xanthomonas campestris, Salmonella typhi, Staphylococcus epidermidis and Listeria monocytogenes was evaluated. Disk diffusion agar, well diffusion agar, minimum inhibitory and bactericidal concentrations and interaction with the antibiotic chloramphenicol were used for this purpose. Increasing the extract concentration from 20 mg/ml to 110 mg/ml significantly increased the antimicrobial activity. The results of disk diffusion agar and well diffusion agar tests showed that the largest diameter of the inhibition zone was for Staphylococcus epidermidis (12.90 mm and 14.37 mm, respectively) and the smallest diameter of the inhibition zone was for Salmonella typhi (9.23 mm and 10.38 mm, respectively). The results of the interaction between dill aqueous extract and the antibiotic chloramphenicol showed that in the combined state of the extract with the antibiotic, a synergistic state was observed for all strains. The antibacterial effect shown by this plant provides a scientific basis and, therefore, confirms its traditional use as a home remedy. Isolation and purification of various phytochemicals may produce significant antibacterial agents.
Article Type:
Original Research |
Subject:
Essences and extracts Received: 2025/01/15 | Accepted: 2025/02/23 | Published: 2025/06/22