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Nowadays the lack of food specially protein is the most important problem. Because of the increasing of  the world population the need for food is increasing day by day for this reason researches are searching for cheap resources of  protein for people. Whey is by- product of  cheese factory. whey provides ecological problems because of  having high COD. According to these problems many researches have been done on whey and different products were achieved such as single cell protein. In this research, the production of  single cell protein from whey and trichosporon yeast are studied in external loop airlift reactor. Effective factors on gas hold up Such as air giving, ratio of  down comer diameter to riser diameter and height of  liquid in gas separator were studied and optimized. In this optimized situation the rate of  single cell protein was achieved. The results of  experiments showed that optimimum value for air giving intensity was 2.27 cm/s , ratio of  down comer diameter to riser diameter was 0/5 cm and height of liquid in gas separator was 3 cm. In this optimum condition, the amount of  single cell protein was 18.9 g/l. The rate of  single cell protein in stirred reactors and bubble column was 10.38 and 17.3 g/l respectively in other^'s researches. In comparison, external loop air lift reactor showed an increase about 8.5 percent to bubble column and 45 percent to stirred reactor in producing single cell protein. So external loop air lift seems suitable in producing single cell protein. producing single cell protein can be studied in Other air lift reactors such as internal loop airlift reactors and obtained results can be campared with the results of  this research.

Keywords: Whey, Key words: Single cell protein, Reactor, Air lift reactor

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